3D Culture and Interferon-γ Priming Modulates Characteristics of Mesenchymal Stromal/Stem Cells by Modifying the Expression of Both Intracellular and Exosomal microRNAs

3D Culture and Interferon-γ Priming Modulates Characteristics of Mesenchymal Stromal/Stem Cells by Modifying the Expression of Both Intracellular and Exosomal microRNAs

Mesenchymal stromal/stem cells (MSCs) have emerged as a therapeutic tool in regenerative medicine. Recent studies have shown that exosome (EXO)-derived microRNAs (miRNAs) play a crucial role in mediating MSC functions. Additionally, intracellular miRNAs have been found to regulate MSC therapeutic ca...

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Bibliographic Details
Main Authors: Matteo Bulati, Alessia Gallo, Giovanni Zito, Rosalia Busà, Gioacchin Iannolo, Nicola Cuscino, Salvatore Castelbuono, Claudia Carcione, Claudio Centi, Gennaro Martucci, Alessandro Bertani, Maria Pia Baiamonte, Cinzia Maria Chinnici, Pier Giulio Conaldi, Vitale Miceli
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biology
Subjects:
mesenchymal stromal/stem cells
microRNAs
MSC priming
IFN-γ priming
MSC spheroids
exosomes
Online Access:https://www.mdpi.com/2079-7737/12/8/1063

Internet

https://www.mdpi.com/2079-7737/12/8/1063

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