Improved oxygen storage capacity of haemoglobin submicron particles by one-pot formulation

The coprecipitation–cross-linking–dissolution (CCD) technique for protein submicron particle fabrication was improved by omitting one preparation step using the macromolecular cross-linker, periodate-oxidized dextran (Odex, M.W. of 40 and 70 kDa). The coprecipitation and cross-linking of haemoglobin...

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Bibliographic Details
Main Authors: Chiraphat Kloypan, Ausanai Prapan, Nittiya Suwannasom, Saranya Chaiwaree, Waraporn Kaewprayoon, Axel Steffen, Yu Xiong, Nuttakorn Baisaeng, Radostina Georgieva, Hans Bäumler
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
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Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2018.1521819