A Multimodal Platform for Simultaneous T-cell Imaging, Defined Activation, and Mechanobiological Characterization

T-cell antigen recognition is accompanied by extensive morphological rearrangements of the contact zone between the T-cell and the antigen-presenting cell (APC). This process involves binding of the T-cell receptor (TCR) complex to antigenic peptides presented via MHC on the APC surface, the interac...

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Bibliographic Details
Main Authors: Martin Fölser, Viktoria Motsch, René Platzer, Johannes B. Huppa, Gerhard J. Schütz
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/235