Molecular defects in primary ciliary dyskinesia are associated with agenesis of the frontal and sphenoid paranasal sinuses and chronic rhinosinusitis

Molecular defects in primary ciliary dyskinesia are associated with agenesis of the frontal and sphenoid paranasal sinuses and chronic rhinosinusitis

Background: Primary ciliary dyskinesia (PCD; MIM 242650) is a rare genetic disorder characterized by malfunction of the motile cilia resulting in reduced mucociliary clearance of the airways. Together with recurring infections of the lower respiratory tract, chronic rhinosinusitis (CRS) is a hallmar...

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Bibliographic Details
Main Authors: Andre Schramm, Johanna Raidt, Anika Gross, Maik Böhmer, Achim Georg Beule, Heymut Omran
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
ciliopathy
PCD
genotype phenotype correlation
sinusitis
health related quality of life
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1258374/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1258374/full

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