Histone Demethylase AMX-1 Regulates Fertility in a p53/CEP-1 Dependent Manner

Histone methylation shapes the epigenetic configuration and adjusts multiple fundamental nuclear processes, including transcription, cell cycle control and DNA repair. The absence of histone demethylase LSD1/SPR-5 leads to progressive fertility defects as well as a reduction in brood size. Similarly...

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Bibliographic Details
Main Authors: Xiaojing Ren, Sisi Tian, Qinghao Meng, Hyun-Min Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.929716/full