JAK Inhibitors and Oxidative Stress Control

JAK Inhibitors and Oxidative Stress Control

Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway improves sicca manifestations. Playing a pri...

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Bibliographic Details
Main Authors: Amandine Charras, Pinelopi Arvaniti, Christelle Le Dantec, George N. Dalekos, Kaliopi Zachou, Anne Bordron, Yves Renaudineau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
primary sjögren's syndrome
ROS
JAK/STAT pathway
ICAM-1
PD-L1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02814/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02814/full

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