Computational Modeling, High-Level Soluble Expression and In Vitro Cytotoxicity Assessment of Recombinant <i>Pseudomonas aeruginosa</i> Azurin: A Promising Anti-Cancer Therapeutic Candidate

Computational Modeling, High-Level Soluble Expression and In Vitro Cytotoxicity Assessment of Recombinant <i>Pseudomonas aeruginosa</i> Azurin: A Promising Anti-Cancer Therapeutic Candidate

Azurin is a natural protein produced by <i>Pseudomonas aeruginosa</i> that exhibits potential anti-tumor, anti-HIV, and anti-parasitic properties. The current study aimed to investigate the potential of azurin protein against breast cancer using both in silico and in vitro analyses. The...

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Bibliographic Details
Main Authors: Shakira Aslam, Hafiz Muzzammel Rehman, Muhammad Zeeshan Sarwar, Ajaz Ahmad, Nadeem Ahmed, Muhammad Imran Amirzada, Hafiz Muhammad Rehman, Humaira Yasmin, Tariq Nadeem, Hamid Bashir
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
azurin
p53
EphB2
cancer therapy
breast cancer
<i>Pseudomonas aeruginosa</i>
Online Access:https://www.mdpi.com/1999-4923/15/7/1825

Internet

https://www.mdpi.com/1999-4923/15/7/1825

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