Use of VacA as a Vaccine Antigen

One of the major toxins secreted by H. pylori is the Vacuolating cytotoxin A (VacA) named after its ability to induce the formation of “vacuole”-like membrane vesicles in the cytoplasm of gastric cells. VacA has been associated with the disruption of mitochondrial functions, stimulation of apoptosis...

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Bibliographic Details
Main Authors: Mati Moyat, Dominique Velin
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/6/181