Use of VacA as a Vaccine Antigen
One of the major toxins secreted by H. pylori is the Vacuolating cytotoxin A (VacA) named after its ability to induce the formation of “vacuole”-like membrane vesicles in the cytoplasm of gastric cells. VacA has been associated with the disruption of mitochondrial functions, stimulation of apoptosis...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-06-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/8/6/181 |