MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity
Abstract Glioblastoma is one of the most common and aggressive brain tumors and has seen few improvements in patient outcomes. Inter-tumor heterogeneity between tumors of different patients as well as intra-tumor heterogeneity of cells within the same tumor challenge the development of effective dru...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-58870-6 |