Evolution driven by a varying host environment selects for distinct HIV-1 entry phenotypes and other informative variants

HIV-1 generates remarkable intra- and inter-host viral diversity during infection. In the response to the dynamic selective pressures of the host’s environment, HIV-1 evolves distinct phenotypes—biological features that provide fitness advantages. The transmitted form of HIV-1 has been shown to requ...

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Bibliographic Details
Main Authors: Shuntai Zhou, Nathan Long, Ronald Swanstrom
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Virology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2023.1291996/full