Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes

The availability of effective, reliably accessible, and affordable treatments for snakebite envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin-specific inhibitors with oral bioavailability used in conjunction with antivenom have been identified as having the poten...

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Bibliographic Details
Main Authors: Matthew R. Lewin, Rebecca W. Carter, Isabel A. Matteo, Stephen P. Samuel, Sunita Rao, Bryan G. Fry, Philip E. Bickler
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/14/11/783