Inducible bronchus-associated lymphoid tissue elicited by a protein cage nanoparticle enhances protection in mice against diverse respiratory viruses.

Destruction of the architectural and subsequently the functional integrity of the lung following pulmonary viral infections is attributable to both the extent of pathogen replication and to the host-generated inflammation associated with the recruitment of immune responses. The presence of antigenic...

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Bibliographic Details
Main Authors: James A Wiley, Laura E Richert, Steve D Swain, Ann Harmsen, Dale L Barnard, Troy D Randall, Mark Jutila, Trevor Douglas, Chris Broomell, Mark Young, Allen Harmsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2743193?pdf=render