Role of cis-trans proline isomerization in the function of pathogenic enterobacterial Periplasmic Binding Proteins.

Periplasmic Binding Proteins (PBPs) trap nutrients for their internalization into bacteria by ABC transporters. Ligand binding triggers PBP closure by bringing its two domains together like a Venus flytrap. The atomic determinants that control PBP opening and closure for nutrient capture and release...

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Detalhes bibliográficos
Principais autores: Paulina Cortes-Hernandez, Lenin Domínguez-Ramírez
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2017-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5708682?pdf=render