A single injection of CM1021, a long half-life hepatocyte growth factor mimetic, increases liver mass in mice
Despite years of positive animal data, hepatocyte growth factor (HGF) has never been developed into a useful pharmaceutical, primarily due to its poor pharmacological properties. CM1021 is a fusion protein containing the K1 loop of HGF and the human IgG1 Fc region. The experiments described here dem...
| Auteur principal: | |
|---|---|
| Format: | Article |
| Langue: | English |
| Publié: |
Elsevier
2021-12-01
|
| Collection: | Biochemistry and Biophysics Reports |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2405580821002806 |