Simplified production and concentration of HIV-1-based lentiviral vectors using HYPERFlask vessels and anion exchange membrane chromatography

<p>Abstract</p> <p>Background</p> <p>During the past twelve years, lentiviral (LV) vectors have emerged as valuable tools for transgene delivery because of their ability to transduce nondividing cells and their capacity to sustain long-term transgene expression in targe...

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Bibliographic Details
Main Authors: Marino Michael P, Puthli Sharon, Kutner Robert H, Reiser Jakob
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/9/10