Platelet-Derived Extracellular Vesicles Promote Tenogenic Differentiation of Stem Cells on Bioengineered Living Fibers

Platelet-Derived Extracellular Vesicles Promote Tenogenic Differentiation of Stem Cells on Bioengineered Living Fibers

Tendon mimetic scaffolds that recreate the tendon hierarchical structure and niche have increasing potential to fully restore tendon functionality. However, most scaffolds lack biofunctionality to boost the tenogenic differentiation of stem cells. In this study, we assessed the role of platelet-deri...

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Bibliographic Details
Main Authors: Ana L. Graça, Rui M. A. Domingues, Manuel Gomez-Florit, Manuela E. Gomes
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
platelets
stem cells
tenogenic differentiation
hierarchical scaffolds
composite living fibers
Online Access:https://www.mdpi.com/1422-0067/24/4/3516

Internet

https://www.mdpi.com/1422-0067/24/4/3516

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