Discovery of U2AF1 neoantigens in myeloid neoplasms

Discovery of U2AF1 neoantigens in myeloid neoplasms

Background Myelodysplastic syndromes (MDS) arise from somatic mutations acquired in hematopoietic stem and progenitor cells, causing cytopenias and predisposing to transformation into secondary acute myeloid leukemia (sAML). Recurrent mutations in spliceosome genes, including U2AF1, are attractive t...

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Bibliographic Details
Main Authors: Marie Bleakley, Ralph Graeme Black, David Wu, Melinda Ann Biernacki, Jessica Lok, Kimberly A Foster, Carrie Cummings, Kyle B Woodward, Tim Monahan, Vivian G Oehler, Derek L Stirewalt, Anthony Rongvaux, Hans Joachim Deeg
Format: Article
Language:English
Published: BMJ Publishing Group 2023-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/12/e007490.full

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https://jitc.bmj.com/content/11/12/e007490.full

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