IFN-gamma regulation of ICAM-1 receptors in bronchial epithelial cells: soluble ICAM–1 release inhibits human rhinovirus infection

<p>Abstract</p> <p>Background</p> <p>Intercellular adhesion molecule-1 (ICAM-1) is a critical target-docking molecule on epithelial cells for 90% of human rhinovirus (HRV) serotypes. Two forms of ICAM-1 exist, membranous (mICAM-1) and soluble (sICAM-1), both expressed b...

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Bibliographic Details
Main Authors: Spiteri Monica A, Whiteman Suzanne C
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/5/1/8