DEHP exposure destroys blood-testis barrier (BTB) integrity of immature testes through excessive ROS-mediated autophagy

DEHP exposure destroys blood-testis barrier (BTB) integrity of immature testes through excessive ROS-mediated autophagy

Di-(2-ethylhexyl) phthalate (DEHP), is known to impair testicular functions and reproduction. However, its effects on immature testis Blood-testis barrier (BTB) and the underlying mechanisms remain obscure. We constructed a rat model to investigate the roles of autophagy in BTB toxicity induced by D...

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Bibliographic Details
Main Authors: W.E.I. Yi, Tang Xiang-Liang, Zhou Yu, Liu Bin, Shen Lian-Ju, Long Chun-lan, L.I.N. Tao, H.E. Da-wei, W.U. Sheng-de, W.E.I. Guang-hui
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-09-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304218300539

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http://www.sciencedirect.com/science/article/pii/S2352304218300539

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