Nafamostat Mesilate Enhances the Radiosensitivity and Reduces the Radiation-Induced Invasive Ability of Colorectal Cancer Cells

Nafamostat Mesilate Enhances the Radiosensitivity and Reduces the Radiation-Induced Invasive Ability of Colorectal Cancer Cells

Neoadjuvant chemoradiotherapy followed by radical surgery is the standard treatment for patients with locally advanced low rectal cancer. However, several studies have reported that ionizing radiation (IR) activates nuclear factor kappa B (NF-κB) that causes radioresistance and induces mat...

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Bibliographic Details
Main Authors: Hiroshi Sugano, Yoshihiro Shirai, Takashi Horiuchi, Nobuhiro Saito, Yohta Shimada, Ken Eto, Tadashi Uwagawa, Toya Ohashi, Katsuhiko Yanaga
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cancers
Subjects:
nafamostat mesilate
colorectal cancer
ionizing radiation
NF-κB
matrix metalloproteinases
Online Access:http://www.mdpi.com/2072-6694/10/10/386

Internet

http://www.mdpi.com/2072-6694/10/10/386

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