Characterization of Forskolin-Induced Ca2+ Signals in Rat Olfactory Receptor Neurons

Forskolin-induced Ca2+ signals were examined in isolated rat olfactory receptor neurons (ORNs) using a Ca2+ indicator, fura-2. In the soma of the ORNs, forskolin caused an increase in the intracellular Ca2+ concentration ([Ca2+]i) that was enhanced by a phosphodiesterase (PDE) 1 inhibitor, 8-methoxy...

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Bibliographic Details
Main Authors: Ken-ichi Otsuguro, Shree Hari Gautam, Shigeo Ito, Yoshiaki Habara, Toshiyuki Saito
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319322339