CryoFIB milling large tissue samples for cryo-electron tomography
Abstract Cryo-electron tomography (cryoET) is a powerful tool for exploring the molecular structure of large organisms. However, technical challenges still limit cryoET applications on large samples. In particular, localization and cutting out objects of interest from a large tissue sample are still...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-32716-z |