Designing double-site lipidated peptide amphiphiles as potent antimicrobial biomaterials to combat multidrug-resistant bacteria

Designing double-site lipidated peptide amphiphiles as potent antimicrobial biomaterials to combat multidrug-resistant bacteria

Rapidly evolving antimicrobial resistance and extremely slow development of new antibiotics have resulted in multidrug-resistant bacterial infections that present a serious threat to human health. Antimicrobial peptides (AMPs) provide promising substitutes, but more research is needed to address sev...

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Bibliographic Details
Main Authors: Zhenheng Lai, Hongyu Chen, Xiaojie Yuan, Jiahui Tian, Na Dong, Xingjun Feng, Anshan Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptides
peptide amphiphiles
double-site lipidated
multidrug-resistant bacteria
stability
mechanism of action
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1074359/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1074359/full

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