Effect of tofacitinib therapy on angiotensin converting enzyme activity in rheumatoid arthritis

Effect of tofacitinib therapy on angiotensin converting enzyme activity in rheumatoid arthritis

IntroductionThe Renin-Angiotensin-Aldosterone system (RAAS) has been implicated in the regulation of the cardiovascular system and linked to rheumatoid arthritis (RA). Little information has become available on the effects of Janus kinase (JAK) inhibition on RAAS. Here we studied the effects of 12-m...

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Main Authors: Dorottya Kacsándi, Miklós Fagyas, Ágnes Horváth, Edit Végh, Anita Pusztai, Monika Czókolyová, Boglárka Soós, Attila Ádám Szabó, Attila Hamar, Zsófia Pethő, Nóra Bodnár, György Kerekes, Katalin Hodosi, Szilvia Szamosi, Gabriella Szűcs, Zoltán Papp, Zoltán Szekanecz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Medicine
Subjects:
rheumatoid arthritis
JAK inhibition
tofacitinib
angiotensin converting enzyme
vascular disease
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1226760/full

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https://www.frontiersin.org/articles/10.3389/fmed.2023.1226760/full

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