GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
Helness et al. show that GFI1/CHD4 complexes critically regulate chromatin accessibility and histone modifications to regulate target genes affecting diverse cellular processes in neutrophils. Their results provide further insight into the molecular network operated by GFI1 for neutrophil differenti...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-12-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02889-2 |