Multi-omics analysis reveals the prognostic and tumor micro-environmental value of lumican in multiple cancer types

Multi-omics analysis reveals the prognostic and tumor micro-environmental value of lumican in multiple cancer types

Background: Lumican (LUM), a proteoglycan of the extracellular matrix, has been reported to be involved in the regulation of immune escape processes, but the data supporting this phenomenon are not sufficient. In this study, we aimed to explore the links among LUM expression, survival, tumor microen...

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Bibliographic Details
Main Authors: Zehuai Guo, Zeyun Li, Ming Chen, Xiangjun Qi, Zhe Sun, Siqi Wu, Xuenan Hou, Mengli Qiu, Yang Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
lumican
pan-cancer
tumor microenvironment
cancer-associated fibroblasts
immunotherapy
multi-omics
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1158747/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1158747/full

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