Correlate tumor mutation burden with immune signatures in human cancers

Abstract Background Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have revealed that high TMB may yield many neoantigens to incite antitumor immune response, a systematic exploration of the correlation between...

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Bibliographic Details
Main Authors: Xiaosheng Wang, Mengyuan Li
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Immunology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12865-018-0285-5