Chronic Ethanol Causes Persistent Increases in Alzheimer’s Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment

Chronic Ethanol Causes Persistent Increases in Alzheimer’s Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment

Epidemiological studies have found that heavy alcohol use is associated with increased risk for Alzheimer’s disease (AD), with frequent drinking earlier in adulthood increasing risk. The increases in neuroinflammation featured in both heavy alcohol use and AD may be partially responsible for this li...

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Bibliographic Details
Main Authors: Autumn E. Tucker, Coral del Mar Alicea Pauneto, Alexandra M. Barnett, Leon G. Coleman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
alcohol
Alzheimer’s disease
neuro-inflammation
abstinence
tau
addiction
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.886634/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2022.886634/full

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