Chronic intermittent hypoxia promotes glomerular hyperfiltration and potentiates hypoxia-evoked decreases in renal perfusion and PO2

Introduction: Sleep apnea (SA) is highly prevalent in patients with chronic kidney disease and may contribute to the development and/or progression of this condition. Previous studies suggest that dysregulation of renal hemodynamics and oxygen flux may play a key role in this process. The present st...

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Bibliographic Details
Main Authors: Kiefer W. Kious, Kalie A. Savage, Stephanie C. E. Twohey, Aubrey F. Highum, Andrew Philipose, Hugo S. Díaz, Rodrigo Del Rio, James A. Lang, Sarah C. Clayton, Noah J. Marcus
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1235289/full