Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK

Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK

Abstract Background The therapeutic armamentarium in multiple myeloma has been significantly broadened by proteasome inhibitors, highly efficient means in controlling of multiple myeloma. Despite the developments of therapeutic regimen in treatment of multiple myeloma, still the complete remission r...

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Bibliographic Details
Main Authors: Azam Salimi, Kema Marlen Schroeder, Mirle Schemionek-Reinders, Margherita Vieri, Saskia Maletzke, Deniz Gezer, Behzad Kharabi Masouleh, Iris Appelmann
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Cancer
Subjects:
Autophagy
Multiple myeloma
Proteasome inhibition
Jnk
Online Access:https://doi.org/10.1186/s12885-022-09775-y

Internet

https://doi.org/10.1186/s12885-022-09775-y

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