Shiga Toxin Glycosphingolipid Receptors in Human Caco-2 and HCT-8 Colon Epithelial Cell Lines

Shiga toxins (Stxs) released by enterohemorrhagic Escherichia coli (EHEC) into the human colon are the causative agents for fatal outcome of EHEC infections. Colon epithelial Caco-2 and HCT-8 cells are widely used for investigating Stx-mediated intestinal cytotoxicity. Only limited data are availabl...

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Bibliographic Details
Main Authors: Ivan U. Kouzel, Gottfried Pohlentz, Julia S. Schmitz, Daniel Steil, Hans-Ulrich Humpf, Helge Karch, Johannes Müthing
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/9/11/338