Optimization of Astilbin Extraction from the Rhizome of Smilax glabra, and Evaluation of Its Anti-Inflammatory Effect and Probable Underlying Mechanism in Lipopolysaccharide-Induced RAW264.7 Macrophages

Optimization of Astilbin Extraction from the Rhizome of Smilax glabra, and Evaluation of Its Anti-Inflammatory Effect and Probable Underlying Mechanism in Lipopolysaccharide-Induced RAW264.7 Macrophages

Astilbin, a dihydroflavonol derivative found in many food and medicine plants, exhibited multiple pharmacological functions. In the present study, the ethanol extraction of astilbin from the rhizome of smilax glabra Roxb was optimized by response surface methodology (RSM) using Box-Behnken design. R...

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Bibliographic Details
Main Authors: Chuan-Li Lu, Yan-Fang Zhu, Meng-Mei Hu, Dong-Mei Wang, Xiao-Jie Xu, Chuan-Jian Lu, Wei Zhu
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Molecules
Subjects:
astilbin
response surface methodology
smilax glabra Rox
anti-inflammatory
inflammatory cytokine
RAW264.7 cell
Online Access:http://www.mdpi.com/1420-3049/20/1/625

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http://www.mdpi.com/1420-3049/20/1/625

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