High-level production and aggregation of hepatitis B surface antigen in transgenic tobacco seeds

The hepatitis B surface antigen (HBsAg) has been successfully produced in tobacco leaves, potato tubers and banana fruits, but at a rather low yield. Plant seeds are well suited for the accumulation, long-time storage and preservation of recombinant proteins with pharmaceutical interest, including a...

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Bibliographic Details
Main Authors: Abel Hernández, Alina López, Yanaysi Ceballo, Lissy Rosabal, Yamilka Rosabal, Kenia Tiel, Marlene Pérez, Ernesto M González, Osmani Ramos, Gil Enríquez
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522013000200002&lng=en&tlng=en