A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass

A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass

ObjectiveTo determine changes in incretins, systemic inflammation, intestinal permeability and microbiome modifications 12 months after metabolic RYGB (mRYGB) in patients with type 2 diabetes (T2D) and their relationship with metabolic improvement.Materials and methodsProspective single-center non-r...

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Bibliographic Details
Main Authors: Laura Hernández-Montoliu, M-Mar Rodríguez-Peña, Rocío Puig, Brenno Astiarraga, Fernando Guerrero-Pérez, Nuria Virgili, Rafael López-Urdiales, Javier Osorio, Rosa Monseny, Claudio Lazzara, Lucía Sobrino, Manuel Pérez-Maraver, María Pérez-Prieto, Silvia Pellitero, Sonia Fernández-Veledo, Joan Vendrell, Nuria Vilarrasa
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
incretin
microbiota
type 2 diabetes remission
severe obesity
bariatric surgery
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1181744/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1181744/full

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