New Russian Trivalent Hepatitis B vaccine (Bubo<sup>®</sup>-Unigep): Phase I Clinical Study Results and Perspectives of Further Investigations Aiming Registration in Russia

Relevance. The absence of a registered vaccine against G145R escape mutant determines the need to develop a drug for the prophylaxis of infectious hepatitis caused by the hepatitis B virus.The aim of the study was to evaluate the safety and reactogenicity of a new hepatitis B recombinant Bubo®-Unige...

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Bibliographic Details
Main Authors: R. Yo. Maksvitis, R. V. Ivanov, A. V. Amelin, A. V. Goncharova, A. S. Andreeva, I. A. Grinyov
Format: Article
Language:Russian
Published: Numikom LLC 2020-01-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/864