Protection against cephalosporin-induced lipid peroxidation and nephrotoxicity by (+)-cyanidanol-3 and vitamin E

Protection against cephalosporin-induced lipid peroxidation and nephrotoxicity by (+)-cyanidanol-3 and vitamin E

The ability of the clinically used cephalosporins: cephalothin, cefotaxime and cefotiam to induce lipid peroxidation (LPO) and renal damage was compared to that of nephrotoxic cephaloridine under in vivo conditions. Glutathione was measured in rat liver or in renal cortex as non-protein sulfhydryls....

Full description

Bibliographic Details
Main Authors: C. Cojocel, K.-L. Tolle, H. El-Hajj, K. Baumann
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2007-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Cephalosporins
Glutathione depletion
Lipid peroxidation
Nephrotoxicity
Antioxidants
Vitamin E
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600017

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600017

Similar Items