High Pretreatment Serum PD-L1 Levels Are Associated with Muscle Invasion and Shorter Survival in Upper Tract Urothelial Carcinoma

High Pretreatment Serum PD-L1 Levels Are Associated with Muscle Invasion and Shorter Survival in Upper Tract Urothelial Carcinoma

Programmed death ligand-1 (PD-L1) is an immune checkpoint molecule and a widely used therapeutic target in urothelial cancer. Its circulating, soluble levels (sPD-L1) were recently suggested to be associated with the presence and prognosis of various malignancies but have not yet been investigated i...

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Bibliographic Details
Main Authors: Ádám Széles, Petra Terézia Kovács, Anita Csizmarik, Melinda Váradi, Péter Riesz, Tamás Fazekas, Szilárd Váncsa, Péter Hegyi, Csilla Oláh, Stephan Tschirdewahn, Christopher Darr, Ulrich Krafft, Viktor Grünwald, Boris Hadaschik, Orsolya Horváth, Péter Nyirády, Tibor Szarvas
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
upper tract urothelial carcinoma
UTUC
sPD-L1
soluble programmed death ligand-1
biomarker
prognosis
Online Access:https://www.mdpi.com/2227-9059/10/10/2560

Internet

https://www.mdpi.com/2227-9059/10/10/2560

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