A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus
ABSTRACT During aerobic growth, S. aureus relies on acetate overflow metabolism, a process where glucose is incompletely oxidized to acetate, for its bioenergetic needs. Acetate is not immediately captured as a carbon source and is excreted as waste by cells. The underlying factors governing acetate...
Հիմնական հեղինակներ: | , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
American Society for Microbiology
2025-01-01
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Շարք: | mSphere |
Խորագրեր: | |
Առցանց հասանելիություն: | https://journals.asm.org/doi/10.1128/msphere.00883-24 |