RUNX1 Upregulates CENPE to Promote Leukemic Cell Proliferation

RUNX1 Upregulates CENPE to Promote Leukemic Cell Proliferation

RUNX1 is a Runt family transcription factor that plays a critical role in normal hematopoiesis, including the differentiation and proliferation of hematopoietic cells. RUNX1 mutations, including chromosomal translocations, cause abnormal cell differentiation, but the mutation alone is not sufficient...

Full description

Bibliographic Details
Main Authors: Shan Liu, Jianyu Yang, Guohuan Sun, Yawen Zhang, Cong Cheng, Jin Xu, Kuangyu Yen, Ting Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Runx1
leukemia cell
cell cycle
apoptosis
differentiation potential
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.692880/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.692880/full

Similar Items