Comparative Analysis of the Mutation and Expression Profile of the Cytoprotective NRF2/ KEAP1/P62/SQSTM1 Signaling Pathway in Different Glioma Subtypes: An In Silico Study
Aim:The NRF2/KEAP1/p62/SQSTM1 pathway is the master regulator of antioxidant enzymes and detoxification proteins, both of which play a critical role in redox homeostasis. It shows that the this structurally active pathway has a crucial role in cancer as it inhibits tumorigenesis and metastatic proce...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Galenos Yayincilik
2023-03-01
|
Series: | Namık Kemal Tıp Dergisi |
Subjects: | |
Online Access: |
http://namikkemalmedj.com/archives/archive-detail/article-preview/comparative-analysis-of-the-mutation-and-expressio/58941
|