Comparative Analysis of the Mutation and Expression Profile of the Cytoprotective NRF2/ KEAP1/P62/SQSTM1 Signaling Pathway in Different Glioma Subtypes: An In Silico Study

Aim:The NRF2/KEAP1/p62/SQSTM1 pathway is the master regulator of antioxidant enzymes and detoxification proteins, both of which play a critical role in redox homeostasis. It shows that the this structurally active pathway has a crucial role in cancer as it inhibits tumorigenesis and metastatic proce...

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Bibliographic Details
Main Authors:	Dilara Fatma AKIN, Sedef Hande AKTAŞ
Format:	Article
Language:	English
Published:	Galenos Yayincilik 2023-03-01
Series:	Namık Kemal Tıp Dergisi
Subjects:	nrf2/keap1/p62/sqstm1 signaling pathway glioma mutation gene expression oxidative stress
Online Access:	http://namikkemalmedj.com/archives/archive-detail/article-preview/comparative-analysis-of-the-mutation-and-expressio/58941

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