LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB)

LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB)

Abstract Inner ear disorders are a cluster of diseases that cause hearing loss in more than 1.5 billion people worldwide. However, the presence of the blood-labyrinth barrier (BLB) on the surface of the inner ear capillaries greatly hinders the effectiveness of systemic drugs for prevention and inte...

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Bibliographic Details
Main Authors: Xi Shi, Zihao Wang, Wei Ren, Long Chen, Cong Xu, Menghua Li, Shiyong Fan, Yuru Xu, Mengbing Chen, Fanjun Zheng, Wenyuan Zhang, Xinbo Zhou, Yue Zhang, Shiwei Qiu, Liyuan Wu, Peng Zhou, Xinze Lv, Tianyu Cui, Yuehua Qiao, Hui Zhao, Weiwei Guo, Wei Chen, Song Li, Wu Zhong, Jian Lin, Shiming Yang
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-00995-z

Internet

https://doi.org/10.1038/s41392-022-00995-z

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