USP28 facilitates pancreatic cancer progression through activation of Wnt/β-catenin pathway via stabilising FOXM1

Abstract Ubiquitination is an important post-translational modification that can be reversed by a family of enzymes called deubiquitinating enzymes (DUBs). Ubiquitin-specific protease 28 (USP28), a member of the DUBs family, functions as a potential tumour promoter in various cancers. However, the b...

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Bibliographic Details
Main Authors: Leifeng Chen, Zheng Xu, Qing Li, Qian Feng, Cihua Zheng, Yunyan Du, Rongfa Yuan, Xiaogang Peng
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04163-z