<i>Polygonatum sibiricum</i> Polysaccharides Attenuate Lipopoly-Saccharide-Induced Septic Liver Injury by Suppression of Pyroptosis via NLRP3/GSDMD Signals

<i>Polygonatum sibiricum</i> Polysaccharides Attenuate Lipopoly-Saccharide-Induced Septic Liver Injury by Suppression of Pyroptosis via NLRP3/GSDMD Signals

Sepsis is a systemic inflammatory response syndrome with high mortality. Acute liver injury is an independent predictor for poor prognosis in septic patients. <i>Polygonatum sibiricum</i> polysaccharides (PSP) have been reported to possess anti-inflammatory and hepatoprotective activitie...

Full description

Bibliographic Details
Main Authors: Linxia Xiao, Liang Qi, Guozhe Zhang, Hongxia Liu, Yaqin Gu, Lihu Zhang, Mingguang Zhang, Hongyan Wu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
sepsis
acute liver injury
<i>Polygonatum sibiricum</i> polysaccharides
pyroptosis
GSDMD
NLRP3
Online Access:https://www.mdpi.com/1420-3049/27/18/5999

Internet

https://www.mdpi.com/1420-3049/27/18/5999

Similar Items