Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position

Early ascidian embryos have a cortical subdomain of endoplasmic reticulum (ER) that controls asymmetric spindle positioning driving unequal cell division. Here the authors show that the microtubule depolymerase Kif2 is localized to a cortical subdomain of the ER that is involved in asymmetric spindl...

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Bibliographic Details
Main Authors: Vlad Costache, Celine Hebras, Gerard Pruliere, Lydia Besnardeau, Margaux Failla, Richard R. Copley, David Burgess, Janet Chenevert, Alex McDougall
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01048-8