Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position
Early ascidian embryos have a cortical subdomain of endoplasmic reticulum (ER) that controls asymmetric spindle positioning driving unequal cell division. Here the authors show that the microtubule depolymerase Kif2 is localized to a cortical subdomain of the ER that is involved in asymmetric spindl...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-01048-8 |
| _version_ | 1818751859183058944 |
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| author | Vlad Costache Celine Hebras Gerard Pruliere Lydia Besnardeau Margaux Failla Richard R. Copley David Burgess Janet Chenevert Alex McDougall |
| author_facet | Vlad Costache Celine Hebras Gerard Pruliere Lydia Besnardeau Margaux Failla Richard R. Copley David Burgess Janet Chenevert Alex McDougall |
| author_sort | Vlad Costache |
| collection | DOAJ |
| description | Early ascidian embryos have a cortical subdomain of endoplasmic reticulum (ER) that controls asymmetric spindle positioning driving unequal cell division. Here the authors show that the microtubule depolymerase Kif2 is localized to a cortical subdomain of the ER that is involved in asymmetric spindle positioning. |
| first_indexed | 2024-12-18T04:42:15Z |
| format | Article |
| id | doaj.art-f449fc479df944e5b2d3c3e94f8c1cb2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:42:15Z |
| publishDate | 2017-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-f449fc479df944e5b2d3c3e94f8c1cb22022-12-21T21:20:42ZengNature PortfolioNature Communications2041-17232017-10-018111310.1038/s41467-017-01048-8Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle positionVlad Costache0Celine Hebras1Gerard Pruliere2Lydia Besnardeau3Margaux Failla4Richard R. Copley5David Burgess6Janet Chenevert7Alex McDougall8Sorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueBoston College, Biology DepartmentSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueSorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Observatoire OcéanologiqueEarly ascidian embryos have a cortical subdomain of endoplasmic reticulum (ER) that controls asymmetric spindle positioning driving unequal cell division. Here the authors show that the microtubule depolymerase Kif2 is localized to a cortical subdomain of the ER that is involved in asymmetric spindle positioning.https://doi.org/10.1038/s41467-017-01048-8 |
| spellingShingle | Vlad Costache Celine Hebras Gerard Pruliere Lydia Besnardeau Margaux Failla Richard R. Copley David Burgess Janet Chenevert Alex McDougall Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position Nature Communications |
| title | Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position |
| title_full | Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position |
| title_fullStr | Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position |
| title_full_unstemmed | Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position |
| title_short | Kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position |
| title_sort | kif2 localizes to a subdomain of cortical endoplasmic reticulum that drives asymmetric spindle position |
| url | https://doi.org/10.1038/s41467-017-01048-8 |
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