Oxaliplatin treatment changes the function of sensory nerves in rats

Oxaliplatin (L-OHP) is a platinum-based chemotherapy drug, used in standard treatment of colorectal cancer. L-OHP frequently causes acute peripheral neuropathies. These adverse effects limit cancer therapy with L-OHP. The present study was designed to reveal the changes in sensory nerve function in...

Full description

Bibliographic Details
Main Authors: Shohei Yamamoto, Hideki Ono, Kazuhiko Kume, Masahiro Ohsawa
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315002443