Obese female mice do not exhibit overt hyperuricemia despite hepatic steatosis and impaired glucose tolerance

Obese female mice do not exhibit overt hyperuricemia despite hepatic steatosis and impaired glucose tolerance

Recent reports have clearly demonstrated a tight correlation between obesity and elevated circulating uric acid levels (hyperuricemia). However, nearly all preclinical work in this area has been completed with male mice, leaving the field with a considerable gap in knowledge regarding female respons...

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Bibliographic Details
Main Authors: Sara E. Lewis, Lihua Li, Marco Fazzari, Sonia R. Salvatore, Jiang Li, Emily A. Hileman, Brooke A. Maxwell, Francisco J. Schopfer, Gavin E. Arteel, Nicholas K.H. Khoo, Eric E. Kelley
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Advances in Redox Research
Subjects:
Uric acid
Xanthine oxidoreductase
Female mice
Diet-induced obesity
Hepatic steatosis
Impaired glucose tolerance
Online Access:http://www.sciencedirect.com/science/article/pii/S2667137922000236

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http://www.sciencedirect.com/science/article/pii/S2667137922000236

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