Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Accumulating evidence indicates the occurrence and development of diabetic complications relates to not only constant high plasma glucose, but also glucose fluctuations which affect various kinds of molecular mechanisms in various target cells and tissues. In this review, we detail reactive oxygen s...

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Manylion Llyfryddiaeth
Prif Awduron:	Zhen-Ye Zhang, Ling-Feng Miao, Ling-Ling Qian, Ning Wang, Miao-Miao Qi, Yu-Min Zhang, Shi-Peng Dang, Ying Wu, Ru-Xing Wang
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Frontiers Media S.A. 2019-09-01
Cyfres:	Frontiers in Endocrinology
Pynciau:	glucose fluctuations diabetes reactive oxygen species protein kinase C protein kinase B mitogen-activated protein kinase
Mynediad Ar-lein:	https://www.frontiersin.org/article/10.3389/fendo.2019.00640/full

Eitemau Tebyg

Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
gan: Cao, Jia-ning, et al.
Cyhoeddwyd: (2010)

Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt
gan: Zhen-Ye Zhang, et al.
Cyhoeddwyd: (2024-09-01)

Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways
gan: Dorothea Schweiger, et al.
Cyhoeddwyd: (2007-03-01)

The Solanum chacoense Fertilization-Related Kinase 3 (ScFRK3) is involved in male and female gametophyte development
gan: Caroline Daigle, et al.
Cyhoeddwyd: (2019-05-01)

Protein Kinases as Drug Development Targets for Heart Disease Therapy
gan: Alison L. Müller, et al.
Cyhoeddwyd: (2010-07-01)

Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways
gan: Yu-Qin Zhao, et al.
Cyhoeddwyd: (2019-11-01)

Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway
gan: Aisha Alhaddad, et al.
Cyhoeddwyd: (2023-03-01)

Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect
gan: Che-Chung Yeh, et al.
Cyhoeddwyd: (2017-11-01)

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes
gan: Kai-yuan JI, et al.
Cyhoeddwyd: (2023-04-01)

PeMPK17 interacts with PeMKK7 and participates in para-hydroxybenzoic acid stress resistance by removing reactive oxygen species
gan: Yajie Niu, et al.
Cyhoeddwyd: (2023-09-01)

MAPK immunoreactivity in streptozotocin-induced diabetic rat testis
gan: Yelız Bozdemır Donmez, et al.
Cyhoeddwyd: (2014-10-01)

Overexpression of SIMK in menadione-treated alfalfa enhances antioxidant machinery and leads to oxidative stress resistance
gan: Jiří Sojka, et al.
Cyhoeddwyd: (2024-12-01)

Identification of a Spotted Leaf Sheath Gene Involved in Early Senescence and Defense Response in Rice
gan: Dongryung Lee, et al.
Cyhoeddwyd: (2018-09-01)

ARABIDOPSIS ATMKK1 KNOCKOUT MUTANT FLOWERS UNDER SHORT DAY CONDITIONS
gan: Chad CONROY, et al.
Cyhoeddwyd: (2024-12-01)

Remodeling tumor‐associated macrophage for anti‐cancer effects by rational design of irreversible inhibition of mitogen‐activated protein kinase‐activated protein kinase 2
gan: Danyi Wang, et al.
Cyhoeddwyd: (2024-07-01)

Bilateral Subretinal Fluid Accumulation during Erdafitinib Therapy
gan: Rajneesh Singh, et al.
Cyhoeddwyd: (2024-09-01)

Modulation of HERG K+ Channels by Chronic Exposure to Activators and Inhibitors of PKA and PKC: Actions Independent of PKA and PKC Phosphorylation
gan: Liliang Shu, et al.
Cyhoeddwyd: (2013-12-01)

GmMPK6 Positively Regulates Salt Tolerance through Induction of <i>GmRbohI1</i> in Soybean
gan: Seungmin Son, et al.
Cyhoeddwyd: (2023-02-01)

Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid
gan: Bodil Bjørndal, et al.
Cyhoeddwyd: (2002-10-01)

Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based influenza model
gan: Si Chen, et al.
Cyhoeddwyd: (2025-01-01)

Effects of Selenium in the MAPK Signaling Cascade
gan: Nadereh Rashtchizadeh, et al.
Cyhoeddwyd: (2015-09-01)

Luteolin, quercetin, genistein and quercetagetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in H9c2 cardiomyoblasts
gan: Gloria Gutiérrez-Venegas, et al.
Cyhoeddwyd: (2017-09-01)

The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
gan: Viswanathan Saraswathi, et al.
Cyhoeddwyd: (2006-07-01)

Ceramide regulation of nuclear protein imports⃞
gan: Randolph S. Faustino, et al.
Cyhoeddwyd: (2008-03-01)

Intermittent High Glucose Enhances the Proliferation of Rat Aortic Vascular Smooth Muscle Cells More Than Constant High Glucose via the Mitogen-Activated Protein Kinase Pathway
gan: Sung Hoon Yu, et al.
Cyhoeddwyd: (2017-09-01)

Kinase drug discovery /
gan: Ward, Richard A., et al.
Cyhoeddwyd: (c201)

Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients
gan: Rafiee Mohammad, et al.
Cyhoeddwyd: (2016-07-01)

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
gan: Sergey Filippov, et al.
Cyhoeddwyd: (2013-08-01)

Control of host cell phosphorylation by Legionella pneumophila
gan: Eva eHaenssler, et al.
Cyhoeddwyd: (2011-04-01)

Eight Weeks of Swimming Training and CBD Oil Consumption Downregulates the Expression of MAPK and PPARα Genes in the Heart Tissue of Myocardial Infarction Rats
gan: Ali Mohammadnia, et al.
Cyhoeddwyd: (2021-09-01)

Pharmacological implications from the adhesion-induced signaling profiles in cultured human retinal pigment epithelial cells
gan: Wen-Chuan Wu, et al.
Cyhoeddwyd: (2014-01-01)

Losmapimod Protected Epileptic Rats From Hippocampal Neuron Damage Through Inhibition of the MAPK Pathway
gan: Min Li, et al.
Cyhoeddwyd: (2019-06-01)

MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury
gan: Yu B, et al.
Cyhoeddwyd: (2023-03-01)

Yomogin, Isolated from <i>Artemisia iwayomogi</i>, Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway
gan: Jin Hee Kim, et al.
Cyhoeddwyd: (2022-12-01)

Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
gan: Zhengqiu Zhou, et al.
Cyhoeddwyd: (2017-04-01)

The MAP Kinase Kinase Gene AbSte7 Regulates Multiple Aspects of Alternaria brassicicola Pathogenesis
gan: Kai Lu, et al.
Cyhoeddwyd: (2019-04-01)

Function of Protein Kinases in Leaf Senescence of Plants
gan: Fengbo Yang, et al.
Cyhoeddwyd: (2022-04-01)

Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis
gan: Xiaoying Yao, et al.
Cyhoeddwyd: (2022-07-01)

Abl family kinases in development and disease /
gan: Koleske, Anthony J.
Cyhoeddwyd: (2006)

Pharmacological inhibition of the MAP2K7 kinase in human disease
gan: H. Daniel Lacorazza
Cyhoeddwyd: (2024-12-01)