Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling

Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling

Abstract Background CLCA2 was reported as a tumor suppressor and disregulated in breast cancer. However, its function in tumor growth and metastasis in NPC has rarely been reported. In this study, we investigated the functional and molecular mechanisms by which CLCA2 influences NPC. Methods CLCA2 ex...

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Bibliographic Details
Main Authors: Yuan-Yuan Qiang, Chang-Zhi Li, Rui Sun, Li-Sheng Zheng, Li-Xia Peng, Jun-Ping Yang, Dong-Fang Meng, Yan-Hong Lang, Yan Mei, Ping Xie, Liang Xu, Yun Cao, Wen-Wen Wei, Li Cao, Hao Hu, Qin Yang, Dong-Hua Luo, Ying-Ying Liang, Bi-Jun Huang, Chao-Nan Qian
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Nasopharyngeal carcinoma
CLCA2
Metastasis
Prognostics
FAK/ERK
Online Access:http://link.springer.com/article/10.1186/s13046-018-0692-8

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http://link.springer.com/article/10.1186/s13046-018-0692-8

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